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Impaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats
AIM: To determine whether mitochondrial dysfunction resulting from high-fat diet is related to impairment of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt, also known as PKB) pathway. METHODS: Rat models of nonalcoholic fatty liver were established by high-fat diet feeding. The expr...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Baishideng Publishing Group Co., Limited
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3012583/ https://ncbi.nlm.nih.gov/pubmed/21182226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i48.6111 |
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