Antibody targeting KIT as pretransplantation conditioning in immunocompetent mice

Inherited hematologic defects that lack an in vivo selective advantage following gene correction may benefit from effective yet minimally toxic cytoreduction of endogenous hematopoietic stem cells (HSCs) prior to transplantation of gene-modified HSCs. We studied the efficacy of administering a novel...

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Detalhes bibliográficos
Main Authors: Xue, Xingkui, Pech, Nancy K., Shelley, W. Christopher, Srour, Edward F., Yoder, Mervin C., Dinauer, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012550/
https://ncbi.nlm.nih.gov/pubmed/20813896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-295949
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