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Treatment of Early and Established Cryptococcus neoformans Infection with Radiolabeled Antibodies in Immunocompetent Mice

We investigated the utility of radioimmunotherapy (RIT) in early and established cryptococcal infection in immunocompetent mice. RIT with (213)Bi-18B7 antibody completely eliminated fungus from mouse lungs and brains for early infection, while (188)Re-18B7 significantly reduced CFU in the lungs or b...

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Detalhes bibliográficos
Main Authors: Jiang, Zewei, Bryan, Ruth A., Morgenstern, Alfred, Bruchertseifer, Frank, Casadevall, Arturo, Dadachova, Ekaterina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256063/
https://ncbi.nlm.nih.gov/pubmed/22005995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00473-11
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