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Treatment of Early and Established Cryptococcus neoformans Infection with Radiolabeled Antibodies in Immunocompetent Mice

We investigated the utility of radioimmunotherapy (RIT) in early and established cryptococcal infection in immunocompetent mice. RIT with (213)Bi-18B7 antibody completely eliminated fungus from mouse lungs and brains for early infection, while (188)Re-18B7 significantly reduced CFU in the lungs or b...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jiang, Zewei, Bryan, Ruth A., Morgenstern, Alfred, Bruchertseifer, Frank, Casadevall, Arturo, Dadachova, Ekaterina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256063/
https://ncbi.nlm.nih.gov/pubmed/22005995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00473-11
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