Radioimmunotherapy Is Effective against High-Inoculum Cryptococcus neoformans Infection in Mice and Does Not Select for Radiation-Resistant Cryptococcal Cells

We investigated the utility of radioimmunotherapy (RIT) in the treatment of experimental cryptococcal infection with high-inoculum and the possibility of RIT treatment selecting for fungal cells with radiation-resistant phenotypes. RIT reduced mortality in high-burden infections, and we found no evi...

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Autors principals: Bryan, Ruth A., Jiang, Zewei, Huang, Xianchun, Morgenstern, Alfred, Bruchertseifer, Frank, Sellers, Rani, Casadevall, Arturo, Dadachova, Ekaterina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663079/
https://ncbi.nlm.nih.gov/pubmed/19139285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01334-08
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