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Anti-tumor activity of an anti-endoglin monoclonal antibody is enhanced in immunocompetent mice
In the present study, we investigated the mechanisms by which anti-endoglin (EDG; CD105) monoclonal antibodies (mAbs) suppress angiogenesis and tumor growth. Antihuman EDG mAb SN6j specifically bound to murine endothelial cells and was internalized into the cells in vitro. SN6j effectively suppresse...
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| Publicado no: | Int J Cancer |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352952/ https://ncbi.nlm.nih.gov/pubmed/18224682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23314 |
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