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Anti-tumor activity of an anti-endoglin monoclonal antibody is enhanced in immunocompetent mice

In the present study, we investigated the mechanisms by which anti-endoglin (EDG; CD105) monoclonal antibodies (mAbs) suppress angiogenesis and tumor growth. Antihuman EDG mAb SN6j specifically bound to murine endothelial cells and was internalized into the cells in vitro. SN6j effectively suppresse...

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Bibliografische gegevens
Gepubliceerd in:Int J Cancer
Hoofdauteurs: Tsujie, Masanori, Tsujie, Tomoko, Toi, Hirofumi, Uneda, Shima, Shiozaki, Ken, Tsai, Hilda, Seon, Ben K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352952/
https://ncbi.nlm.nih.gov/pubmed/18224682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23314
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