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Mechanism of tungsten-dependent acetylene hydratase from quantum chemical calculations

Acetylene hydratase is a tungsten-dependent enzyme that catalyzes the nonredox hydration of acetylene to acetaldehyde. Density functional theory calculations are used to elucidate the reaction mechanism of this enzyme with a large model of the active site devised on the basis of the native X-ray cry...

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Autores principales: Liao, Rong-Zhen, Yu, Jian-Guo, Himo, Fahmi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012519/
https://ncbi.nlm.nih.gov/pubmed/21149684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014060108
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