L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability

The l3mbtl1 gene is located on the long arm of chromosome 20 (q12), within a region commonly deleted in several myeloid malignancies. L3MBTL1 is a human homolog of the Drosophila polycomb L(3)MBT tumor suppressor protein and thus a candidate tumor suppressor in del(20q12) myeloid disorders. We used...

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Main Authors: Gurvich, Nadia, Perna, Fabiana, Farina, Andrea, Voza, Francesca, Menendez, Silvia, Hurwitz, Jerard, Nimer, Stephen D.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012470/
https://ncbi.nlm.nih.gov/pubmed/21149733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017092108
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