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Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1

Lethal 3 malignant brain tumor 1 (L3MBTL1), a homolog of the Drosophila polycomb tumor suppressor l(3)mbt, contains three tandem MBT repeats (3xMBT) that are critical for transcriptional repression. We recently reported that the 3xMBT repeats interact with mono- and dimethylated lysines in the amino...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kalakonda, N, Fischle, W, Boccuni, P, Gurvich, N, Hoya-Arias, R, Zhao, X, Miyata, Y, MacGrogan, D, Zhang, J, Sims, JK, Rice, JC, Nimer, SD
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742506/
https://ncbi.nlm.nih.gov/pubmed/18408754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.67
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