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Functional Roles of Multiple Feedback Loops in ERK and Wnt Signaling Pathways that Regulate Epithelial-Mesenchymal Transition
Epithelial-mesenchymal transition (EMT) is a key event in the generation of invasive tumor cells. A hallmark of EMT is the repression of E-cadherin expression, which is regulated by various signal transduction pathways including extracellular signal regulated-kinase (ERK) and Wnt. These pathways are...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3012452/ https://ncbi.nlm.nih.gov/pubmed/20736375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1377 |
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