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A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer
Epithelial-mesenchymal transition (EMT) is an important biologic process that has been implicated in cancer metastasis. Epithelial cell adhesion molecule (EpCAM) is expressed at the basolateral membrane of most normal epithelial cells, but is overexpressed in many epithelial cancers. In our studies...
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| Publicat a: | Oncogene |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5571977/ https://ncbi.nlm.nih.gov/pubmed/28192403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.504 |
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