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A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer
Epithelial-mesenchymal transition (EMT) is an important biologic process that has been implicated in cancer metastasis. Epithelial cell adhesion molecule (EpCAM) is expressed at the basolateral membrane of most normal epithelial cells, but is overexpressed in many epithelial cancers. In our studies...
Kaydedildi:
| Yayımlandı: | Oncogene |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5571977/ https://ncbi.nlm.nih.gov/pubmed/28192403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.504 |
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