Persistent activation of STAT3 by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer

Metastasis of breast cancer is promoted by epithelial–mesenchymal transition (EMT). Emerging evidence suggests that STAT3 is a critical signaling node in EMT and is constitutively activated in many carcinomas, including breast cancer. However, its signaling mechanisms underlying persistent activatio...

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Publicado en:Cancer Sci
Autores principales: Uddin, Nizam, Kim, Rae-Kwon, Yoo, Ki-Chun, Kim, Young-Heon, Cui, Yan-Hong, Kim, In-Gyu, Suh, Yongjoon, Lee, Su-Jae
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471798/
https://ncbi.nlm.nih.gov/pubmed/25854938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12668
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