Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?

OBJECTIVE: Lipotoxicity and ectopic fat deposition reduce insulin signaling. It is not clear whether excess fat deposition in nonadipose tissue arises from excessive fatty acid delivery from adipose tissue or from impaired adipose tissue storage of ingested fat. RESEARCH DESIGN AND METHODS: To inves...

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Autors principals: McQuaid, Siobhán E., Hodson, Leanne, Neville, Matthew J., Dennis, A. Louise, Cheeseman, Jane, Humphreys, Sandy M., Ruge, Toralph, Gilbert, Marjorie, Fielding, Barbara A., Frayn, Keith N., Karpe, Fredrik
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2011
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012196/
https://ncbi.nlm.nih.gov/pubmed/20943748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0867
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