Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?

OBJECTIVE: Lipotoxicity and ectopic fat deposition reduce insulin signaling. It is not clear whether excess fat deposition in nonadipose tissue arises from excessive fatty acid delivery from adipose tissue or from impaired adipose tissue storage of ingested fat. RESEARCH DESIGN AND METHODS: To inves...

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Main Authors: McQuaid, Siobhán E., Hodson, Leanne, Neville, Matthew J., Dennis, A. Louise, Cheeseman, Jane, Humphreys, Sandy M., Ruge, Toralph, Gilbert, Marjorie, Fielding, Barbara A., Frayn, Keith N., Karpe, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2011
Assuntos:
Metabolism
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012196/
https://ncbi.nlm.nih.gov/pubmed/20943748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0867
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