The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm.
In Saccharomyces cerevisiae the UPF1 protein is required for nonsense-mediated mRNA decay, the accelerated turnover of mRNAs containing a nonsense mutation. Several lines of evidence suggest that translation plays an important role in the mechanism of nonsense mRNA decay, including a previous report...
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| Udgivet i: | Mol Biol Cell |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Cell Biology
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7545033/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.5.611 |
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