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Cyclic GMP Kinase I Modulates Glucagon Release From Pancreatic α-Cells

OBJECTIVE: The physiologic significance of the nitric oxide (NO)/cGMP signaling pathway in islets is unclear. We hypothesized that cGMP-dependent protein kinase type I (cGKI) is directly involved in the secretion of islet hormones and glucose homeostasis. RESEARCH DESIGN AND METHODS: Gene-targeted m...

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Detalhes bibliográficos
Main Authors: Leiss, Veronika, Friebe, Andreas, Welling, Andrea, Hofmann, Franz, Lukowski, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012166/
https://ncbi.nlm.nih.gov/pubmed/20978093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0595
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