Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis

INTRODUCTION: Intestinal epithelial expression of anti-oxidants and NF-κB contribute to mucosal barrier integrity and epithelial homoestasis, two key events in the pathogenesis of inflammatory bowel disease. Genetic restoration of intestinal epithelial prohibitin 1 (PHB) levels during experimental c...

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Autori principali: Theiss, Arianne L., Laroui, Hamed, Obertone, Tracy S., Chowdhury, Indrajit, Thompson, Winston E., Merlin, Didier, Sitaraman, Shanthi V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012155/
https://ncbi.nlm.nih.gov/pubmed/20872832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21469
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