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Coordinated Translocation of Mammalian Gli Proteins and Suppressor of Fused to the Primary Cilium

Intracellular transduction of Hedgehog (Hh) signals in mammals requires functional primary cilia. The Hh signaling effectors, the Gli family of transcription factors, and their negative regulator, Suppressor of Fused (Sufu), accumulate at the tips of cilia; however, the molecular mechanism regulatin...

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Bibliografiska uppgifter
Huvudupphovsmän: Zeng, Huiqing, Jia, Jinping, Liu, Aimin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012114/
https://ncbi.nlm.nih.gov/pubmed/21209912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015900
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