Simvastatin impairs murine melanoma growth

BACKGROUND: Statins induces cell cycle arrest, apoptosis, reduction of angiogenic factors, inhibition of the endothelial growth factor, impairing tissue adhesion and attenuation of the resistance mechanisms. The aim of this study was evaluate the anti-tumoral activity of simvastatin in a B16F10 mela...

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Detalhes bibliográficos
Main Authors: Favero, Giovani M, F Otuki, Michel, Oliveira, Karen A, Bohatch, Milton S, Borelli, Primavera, Barros, Francisco E, Maria, Durvanei A, Fernandes, Daniel, Bydlowski, Sergio P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012033/
https://ncbi.nlm.nih.gov/pubmed/21162733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-142
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