Cell internalization of 7-ketocholesterol-containing nanoemulsion through LDL receptor reduces melanoma growth in vitro and in vivo: a preliminary report

Oxysterols are cholesterol oxygenated derivatives which possess several biological actions. Among oxysterols, 7-ketocholesterol (7KC) is known to induce cell death. Here, we hypothesized that 7KC cytotoxicity could be applied in cancer therapeutics. 7KC was incorporated into a lipid core nanoemulsio...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Favero, Giovani M., Paz, Jessica L., Otake, Andréia H., Maria, Durvanei A., Caldini, Elia G., de Medeiros, Raphael S.S., Deus, Debora F., Chammas, Roger, Maranhão, Raul C., Bydlowski, Sergio P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865661/
https://ncbi.nlm.nih.gov/pubmed/29581835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24389
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