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Simvastatin reduces melanoma progression in a murine model

Statins are a class of drugs that inhibit the rate-limiting step in the cholesterol biosynthetic pathway and show an anticancer effect, probably through the inhibition of cell proliferation. To date, the exact mechanism of cancer cell growth arrest induced by statins is not known. We report that sim...

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Detalhes bibliográficos
Main Authors: ZANFARDINO, MARIO, SPAMPANATO, CARMINE, DE CICCO, ROSANNA, BUOMMINO, ELISABETTA, DE FILIPPIS, ANNA, BAIANO, SALVATORE, BARRA, ADRIANO, MORELLI, FRANCO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833984/
https://ncbi.nlm.nih.gov/pubmed/24101161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2126
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