AMPK Signaling Results in Cytoplasmic Sequestration of p27

Tuberin, the Tsc2 gene product, integrates PI3K/MAPK (mitogenic) and LKB1/AMPK (energy) signaling pathways, and previous independent studies have shown that loss of tuberin is associated with elevated AMPK signaling and altered p27 function. In Tsc2-null tumors and tumor-derived cells from Eker rats...

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Main Authors: Short, John D., Houston, Kevin D., Dere, Ruhee, Cai, Sheng-Li, Kim, Jinhee, Johnson, Charles L., Broaddus, Russell R., Shen, Jianjun, Miyamoto, Susie, Tamanoi, Fuyuhiko, Kwiatkowski, David, Mills, Gordon B., Walker, Cheryl Lyn
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011867/
https://ncbi.nlm.nih.gov/pubmed/18701472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5756
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