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Solvent effects on the energy landscapes and folding kinetics of polyalanine

The effect of a solvation on the thermodynamics and kinetics of polyalanine (Ala(12)) is explored on the basis of its energy landscapes in vacuum and in an aqueous solution. Both energy landscapes are characterized by two basins, one associated with α-helical structures and the other with coil and β...

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Bibliografiske detaljer
Main Authors: Levy, Yaakov, Jortner, Joshua, Becker, Oren M.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC30113/
https://ncbi.nlm.nih.gov/pubmed/11226214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041611998
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