Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae.

In eukaryotic cells all isoprenoids are synthesized from a common precursor, mevalonate. The formation of mevalonate from 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) is catalyzed by HMG-CoA reductase and is the first committed step in isoprenoid biosynthesis. In mammalian cells, synthesis of HMG...

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Veröffentlicht in:	Mol Biol Cell
Hauptverfasser:	Dimster-Denk, D, Thorsness, M K, Rine, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Cell Biology 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7949422/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.6.655
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