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Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have been used widely for treating human immunodeficiency virus type 1 (HIV-1) infected patients as a component of highly active antiretroviral therapy (HAART) and for the prevention of mother-to-child transmission (MTCT). Cytochrome P450 (CYP...

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Hlavní autoři: Saitoh, Akihiko, Spector, Stephen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010754/
https://ncbi.nlm.nih.gov/pubmed/21197270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/17469600.2.1.69
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