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Impact of Nucleoside Reverse Transcriptase Inhibitors on Mitochondrial DNA and RNA in Human Skeletal Muscle Cells

We previously reported that 2′,3′-dideoxyinosine (didanosine, or ddI) significantly altered mitochondrial DNA (mtDNA) in peripheral blood mononuclear cells in human immunodeficiency virus type 1 (HIV-1)-infected children who had undetectable plasma HIV-1 RNA for more than 2 years while receiving hig...

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Detalhes bibliográficos
Main Authors: Saitoh, Akihiko, Haas, Richard H., Naviaux, Robert K., Salva, Neurita G., Wong, Justine K., Spector, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493104/
https://ncbi.nlm.nih.gov/pubmed/18541728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00434-08
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