STAT3 modulates the DNA damage response pathway

The STAT3 transcription factor is well known to function as an anti-apoptotic factor, especially in numerous malignancies. Recently we showed that STAT3 is cytoprotective and that cells lacking STAT3 are more sensitive to oxidative stress. A key feature of oxidative stress involves activation of the...

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Hlavní autoři: Barry, Seán P, Townsend, Paul A, Knight, Richard A, Scarabelli, Tiziano M, Latchman, David S, Stephanou, Anastasis
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010549/
https://ncbi.nlm.nih.gov/pubmed/20804538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2010.00734.x
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