NF-κB is activated by radiotherapy and is prognostic for overall survival in patients with rectal cancer treated with preoperative fluorouracil-based chemoradiation

PURPOSE: Rectal cancer is often clinically resistant to radiotherapy and there would be value to identifying molecular markers to define the biological basis for this phenomenon. NF-κB is a potentially anti-apoptotic transcription factor that has been associated with resistance to radiotherapy in mo...

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Detalhes bibliográficos
Main Authors: O’Neil, Bert H., Funkhouser, William K., Calvo, Benjamin F., Meyers, Michael O., Kim, Hong Jin, Goldberg, Richard M., Bernard, Stephen A., Caskey, Laura, Deal, Allison M., Wright, Fred, Baldwin, Albert S., Tepper, Joel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010530/
https://ncbi.nlm.nih.gov/pubmed/20630669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2010.02.063
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