NF-κB and Bcl-3 Activation Are Prognostic in Metastatic Colorectal Cancer

PURPOSE: NF-κB is an antiapoptotic transcription factor that has been shown to be a mediator of treatment resistance. Bcl-3 is a regulator of NF-κB that may play a role in oncogenesis. The goal of this study was to correlate the activation status of NF-κB and Bcl-3 with clinical outcome in a group o...

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Detalhes bibliográficos
Main Authors: Puvvada, Soham D., Funkhouser, William K., Greene, Kevin, Deal, Allison, Chu, Haitao, Baldwin, Albert S., Tepper, Joel E., O'Neil, Bert H.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Clinical Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914399/
https://ncbi.nlm.nih.gov/pubmed/20414006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000313697
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