A Phase I Study of Bortezomib in Combination With Standard 5-Fluorouracil and External-Beam Radiation Therapy for the Treatment of Locally Advanced or Metastatic Rectal Cancer

BACKGROUND: Standard therapy for stage II/III rectal cancer consists of a fluoropyrimidine and radiation therapy followed by surgery. Preclinical data demonstrated that bortezomib functions as a radiosensitizer in colorectal cancer models. The purpose of this study was to determine the maximum toler...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: O’Neil, Bert H., Raftery, Laura, Calvo, Benjamin F., Chakravarthy, A. Bapsi, Ivanova, Anastasia, Myers, Michael O., Kim, Hong Jin, Chan, Emily, Wise, Paul E., Caskey, Laura S., Bernard, Stephen A., Sanoff, Hanna K., Goldberg, Richard M., Tepper, Joel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893386/
https://ncbi.nlm.nih.gov/pubmed/20378507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3816/CCC.2010.n.017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados