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Inhibition of APE1/Ref-1 Redox Activity with APX3330 Blocks Retinal Angiogenesis in vitro and in vivo

This study examines the role of APE1/Ref-1 in the retina and its potential as a therapeutic target for inhibiting retinal angiogenesis. APE1/Ref-1 expression was quantified by Western blot. The role of APE1/Ref-1 redox function in endothelial cell in vitro angiogenesis was examined by treating retin...

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Bibliographic Details
Main Authors: Jiang, Aihua, Gao, Hua, Kelley, Mark R., Qiao, Xiaoxi
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010438/
https://ncbi.nlm.nih.gov/pubmed/20937296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2010.10.008
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