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Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines

APE1/Ref-1 is a main regulator of cellular response to oxidative stress via DNA-repair function and co-activating activity on the NF-κB transcription factor. APE1 is central in controlling the oxidative stress-based inflammatory processes through modulation of cytokines expression and its overexpres...

詳細記述

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書誌詳細
主要な著者: Cesaratto, Laura, Codarin, Erika, Vascotto, Carlo, Leonardi, Antonio, Kelley, Mark R., Tiribelli, Claudio, Tell, Gianluca
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744539/
https://ncbi.nlm.nih.gov/pubmed/23967134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070909
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