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Automated Radiochemical Synthesis of [(18)F]FBEM: a Thiol Reactive Synthon for Radiofluorination of Peptides and Proteins

The automated radiochemical synthesis of N-[2-(4-[(18)F]fluorobenzamido)ethyl]maleimide ([(18)F]FBEM, IUPAC name: N-maleoylethyl-4-[(18)F]fluorobenzamide), a prosthetic group for radiolabeling the free sulfhydryl groups of peptides and proteins is herein described. 4-[(18)F]Fluorobenzoic acid was fi...

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Autori principali: Kiesewetter, Dale O., Jacobson, Orit, Lang, Lixin, Chen, Xiaoyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010425/
https://ncbi.nlm.nih.gov/pubmed/20965741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2010.09.023
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