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α-Lipoic Acid Protects Diabetic Apolipoprotien E-deficient Mice from Nephropathy

AIM: Both hyperglycemia and hyperlipidemia increase oxidative stress, and contribute to the development of diabetic nephropathy (DN). We investigated effects of α-lipoic acid, a natural antioxidant and a cofactor in the multienzyme complexes, on the development of DN in diabetic apolipoprotein E-def...

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Main Authors: Yi, Xianwen, Nickeleit, Volker, James, Leighton R, Maeda, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010318/
https://ncbi.nlm.nih.gov/pubmed/20801062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2010.07.004
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