Muscle weakness in Ryr1(I4895T/WT) knock-in mice as a result of reduced ryanodine receptor Ca(2+) ion permeation and release from the sarcoplasmic reticulum

Eitemau Tebyg

• A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca(2+) release in muscle fibers of Y522S RyR1 knock-in mice
  gan: Andronache, Zoita, et al.
  Cyhoeddwyd: (2009)
• Ca(2+) dysregulation in Ryr1(I4895T/wt) mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods
  gan: Zvaritch, Elena, et al.
  Cyhoeddwyd: (2009)
• An Ryr1(I4895T) mutation abolishes Ca(2+) release channel function and delays development in homozygous offspring of a mutant mouse line
  gan: Zvaritch, Elena, et al.
  Cyhoeddwyd: (2007)
• The I4895T Mutation in the Type 1 Ryanodine Receptor Induces Fiber-Type Specific Alterations in Skeletal Muscle that Mimic Premature Aging
  gan: Boncompagni, Simona, et al.
  Cyhoeddwyd: (2010)
• Topology of the Ca(2+) release channel of skeletal muscle sarcoplasmic reticulum (RyR1)
  gan: Du, Guo Guang, et al.
  Cyhoeddwyd: (2002)