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Decorin Antagonizes Met Receptor Activity and Down-regulates β-Catenin and Myc Levels

A theme emerging during the past few years is that members of the small leucine-rich proteoglycan gene family affect cell growth by interacting with multiple receptor tyrosine kinases (RTKs), mostly by a physical down-regulation of the receptors, thereby depriving tumor cells of pro-survival signals...

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Autors principals: Buraschi, Simone, Pal, Nutan, Tyler-Rubinstein, Nadia, Owens, Rick T., Neill, Thomas, Iozzo, Renato V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009933/
https://ncbi.nlm.nih.gov/pubmed/20974860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.172841
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