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An Alternative Pathway for Okazaki Fragment Processing: RESOLUTION OF FOLD-BACK FLAPS BY Pif1 HELICASE
Two pathways have been proposed for eukaryotic Okazaki fragment RNA primer removal. Results presented here provide evidence for an alternative pathway. Primer extension by DNA polymerase δ (pol δ) displaces the downstream fragment into an RNA-initiated flap. Most flaps are cleaved by flap endonuclea...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009898/ https://ncbi.nlm.nih.gov/pubmed/20959454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146894 |
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