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Natural and Engineered Photoactivated Nucleotidyl Cyclases for Optogenetic Applications

Cyclic nucleotides, cAMP and cGMP, are ubiquitous second messengers that regulate metabolic and behavioral responses in diverse organisms. We describe purification, engineering, and characterization of photoactivated nucleotidyl cyclases that can be used to manipulate cAMP and cGMP levels in vivo. W...

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Detaylı Bibliyografya
Asıl Yazarlar: Ryu, Min-Hyung, Moskvin, Oleg V., Siltberg-Liberles, Jessica, Gomelsky, Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009876/
https://ncbi.nlm.nih.gov/pubmed/21030591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177600
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