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Natural and Engineered Photoactivated Nucleotidyl Cyclases for Optogenetic Applications

Cyclic nucleotides, cAMP and cGMP, are ubiquitous second messengers that regulate metabolic and behavioral responses in diverse organisms. We describe purification, engineering, and characterization of photoactivated nucleotidyl cyclases that can be used to manipulate cAMP and cGMP levels in vivo. W...

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Bibliografiske detaljer
Main Authors: Ryu, Min-Hyung, Moskvin, Oleg V., Siltberg-Liberles, Jessica, Gomelsky, Mark
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009876/
https://ncbi.nlm.nih.gov/pubmed/21030591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177600
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