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Axonal Degeneration Is Blocked by Nicotinamide Mononucleotide Adenylyltransferase (Nmnat) Protein Transduction into Transected Axons

Axonal degeneration is an early and important component of many neurological disorders. Overexpression of nicotinamide mononucleotide adenylyltransferase (Nmnat), a component of the slow Wallerian degeneration (Wld(s)) protein, protects axons from a variety of insults. We found that transduction of...

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Autors principals: Sasaki, Yo, Milbrandt, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009846/
https://ncbi.nlm.nih.gov/pubmed/21071441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.193904
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