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Synaptic targeting of AMPA receptors is regulated by a CaMKII site in the first intracellular loop of GluA1

The accumulation of AMPA receptors (AMPARs) at synapses is essential for excitatory synaptic transmission. However, the mechanisms underlying synaptic targeting of AMPARs remain elusive. We have now used a molecular replacement approach on an AMPAR-null background to investigate the targeting mechan...

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Detalhes bibliográficos
Main Authors: Lu, Wei, Isozaki, Kaname, Roche, Katherine W., Nicoll, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009812/
https://ncbi.nlm.nih.gov/pubmed/21135237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016289107
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