Activated CaMKII couples GluN2B and Casein Kinase 2 to control synaptic NMDA Receptors

Synaptic activity triggers a profound reorganization of the molecular composition of excitatory synapses. For example, NMDA receptors are removed from synapses in an activity- and calcium-dependent manner, via casein kinase 2 (CK2) phosphorylation of the PDZ-ligand of the GluN2B subunit (S1480). How...

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Autori principali: Sanz-Clemente, Antonio, Gray, John A., Ogilvie, Kyle A., Nicoll, Roger A., Roche, Katherine W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615108/
https://ncbi.nlm.nih.gov/pubmed/23478024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.011
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