Structure-Function Relationship of Cytoplasmic and Nuclear IκB Proteins: An In Silico Analysis

Cytoplasmic IκB proteins are primary regulators that interact with NF-κB subunits in the cytoplasm of unstimulated cells. Upon stimulation, these IκB proteins are rapidly degraded, thus allowing NF-κB to translocate into the nucleus and activate the transcription of genes encoding various immune med...

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Bibliografske podrobnosti
Main Authors: Manavalan, Balachandran, Basith, Shaherin, Choi, Yong-Min, Lee, Gwang, Choi, Sangdun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009747/
https://ncbi.nlm.nih.gov/pubmed/21203422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015782
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