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Structure-Function Relationship of Cytoplasmic and Nuclear IκB Proteins: An In Silico Analysis
Cytoplasmic IκB proteins are primary regulators that interact with NF-κB subunits in the cytoplasm of unstimulated cells. Upon stimulation, these IκB proteins are rapidly degraded, thus allowing NF-κB to translocate into the nucleus and activate the transcription of genes encoding various immune med...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009747/ https://ncbi.nlm.nih.gov/pubmed/21203422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015782 |
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