Similar Structures but Different Roles – An Updated Perspective on TLR Structures

Toll-like receptors (TLRs) are pattern recognition receptors that recognize conserved structures in pathogens, trigger innate immune responses, and prime antigen-specific adaptive immunity. Elucidation of crystal structures of TLRs interacting with their ligands such as TLR1-2 with triacylated lipop...

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Bibliographic Details
Main Authors: Manavalan, Balachandran, Basith, Shaherin, Choi, Sangdun
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2011
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146039/
https://ncbi.nlm.nih.gov/pubmed/21845181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2011.00041
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