A Role for ATF2 in Regulating MITF and Melanoma Development

The transcription factor ATF2 has been shown to attenuate melanoma susceptibility to apoptosis and to promote its ability to form tumors in xenograft models. To directly assess ATF2's role in melanoma development, we crossed a mouse melanoma model (Nras(Q61K)::Ink4a(−/−)) with mice expressing a...

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Main Authors: Shah, Meera, Bhoumik, Anindita, Goel, Vikas, Dewing, Antimone, Breitwieser, Wolfgang, Kluger, Harriet, Krajewski, Stan, Krajewska, Maryla, DeHart, Jason, Lau, Eric, Kallenberg, David M., Jeong, Hyeongnam, Eroshkin, Alexey, Bennett, Dorothy C., Chin, Lynda, Bosenberg, Marcus, Jones, Nic, Ronai, Ze'ev A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2010
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009656/
https://ncbi.nlm.nih.gov/pubmed/21203491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001258
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