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Physical determinants of strong voltage sensitivity of K(+) channel block
Strong voltage sensitivity of inward-rectifier K(+) (Kir) channels has been hypothesized to arise primarily from an intracellular blocker displacing up to five K(+) ions from the wide, intracellular part of the ion conduction pore outwardly across the narrow ion selectivity filter. The validity of t...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009588/ https://ncbi.nlm.nih.gov/pubmed/19915587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1717 |
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