טוען...
Calculating pK(a) values in the cAMP-dependent protein kinase: The effect of conformational change and ligand binding
The conformational change observed upon ligand binding and phosphorylation for the cAMP-dependent protein kinase (protein kinase A—PKA) is of high importance for the regulation of its activity. We calculate pK(a) values and net charges for 18 3D structures of PKA in various conformations and ligande...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009415/ https://ncbi.nlm.nih.gov/pubmed/20954248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.530 |
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