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A Single Nucleotide Polymorphism in Tyk2 Controls Susceptibility to Experimental Allergic Encephalomyelitis
Genes controlling immunopathologic diseases of differing etiopathology may also influence susceptibility to autoimmune disease. B10.D1-H2(q)/SgJ mice with a 2538 G→A missense mutation in tyrosine kinase-2 (Tyk2) are susceptible to Toxoplasma gondii, yet resistant to autoimmune arthritis, unlike the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008628/ https://ncbi.nlm.nih.gov/pubmed/19494301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900142 |
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