A Single Nucleotide Polymorphism in Tyk2 Controls Susceptibility to Experimental Allergic Encephalomyelitis

Genes controlling immunopathologic diseases of differing etiopathology may also influence susceptibility to autoimmune disease. B10.D1-H2(q)/SgJ mice with a 2538 G→A missense mutation in tyrosine kinase-2 (Tyk2) are susceptible to Toxoplasma gondii, yet resistant to autoimmune arthritis, unlike the...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Spach, Karen M., Noubade, Rajkumar, McElvany, Ben, Hickey, William F., Blankenhorn, Elizabeth P., Teuscher, Cory
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008628/
https://ncbi.nlm.nih.gov/pubmed/19494301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900142
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki