Von-Willebrand Factor Influences Blood Brain Barrier Permeability and Brain Inflammation in Experimental Allergic Encephalomyelitis

Weibel-Palade bodies within endothelial cells are secretory granules known to release von Willebrand Factor (VWF), P-selectin, chemokines, and other stored molecules following histamine exposure. Mice with a disrupted VWF gene (VWFKO) have endothelial cells that are deficient in Weibel-Palade bodies...

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Detalhes bibliográficos
Main Authors: Noubade, Rajkumar, del Rio, Roxana, McElvany, Benjamin, Zachary, James F., Millward, Jason M., Wagner, Denisa D., Offner, Halina, Blankenhorn, Elizabeth P., Teuscher, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526288/
https://ncbi.nlm.nih.gov/pubmed/18688020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080001
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